CNR - ISMN
Research/Research Contracts

Industrial Project

Committente:
CyDex Pharmaceuticals, Inc.
Nome progetto:
Design of Novel Nanogel based on CAPTISOL® and Cationic Photosensitizer as Promising Tools in Photodynamic Therapy
Durata:
12 months
Link:
Ligand Pharmaceuticals

Stimuli-responsive polymeric depots (e.g. through the use of light or magnetic field) promise a substantial improvement in the treatment of many local diseases. Local controlled release technology presents numerous advantages as a better control over drug concentration at disease sites, avoiding off-target side effects. Drug depots can also release drugs for long periods of time (weeks to months), obviating the need for patients to repeatedly dose themselves. The focus of this proposal is the design and characterize of novel photosensitizing biocompatible nanogel based on CAPTISOL® capable to release the therapeutics on-demand. The presence of both a photosensitizer and an anticancer drug ensure a combination action thus inducing photodynamic and anticancer effect. Furthermore, these nanogels can be loaded with magnetic nanoparticles (MNP), which allow the remote control of the response to external magnetic stimuli, possibly by modulating the drug release kinetics.

Industrial Project

Committente:
SIFI FARMACEUTICI
Nome progetto:
Nanostructures as solid lipid delivery systems to the back eye
Durata:
3 anni

Nanostructures as solid lipid delivery systems to the back eye for the treatment of pathologies of the retina. SIFI PHARMACEUTICALS - ISMN-CNR and UNIPA

Industrial Project

Committente:
FIDIA FARMACEUTICI.
Nome progetto:
Lipid nanoparticle-containing compositions and riluzole
Durata:
2 anni

Lipid nanoparticle-containing compositions and riluzole pharmaceutical containing them for the treatment of Amyotrophic Lateral Sclerosis (ALS): targeting to the CNS.
 FIDIA FARMACEUTICI - ISMN-CNR and UNIPA.

Industrial Project

Committente:
PFIZER ITALIA S.R.L.
Nome progetto:
Targeting to the Central Nervous System of cabergoline and donepezil through lipid nanoparticle
Durata:
2 anni

Targeting to the Central Nervous System of cabergoline and donepezil through lipid nanoparticles.  PFIZER ITALY and ISMN-CNR.  Objective: To obtain a greater targeting of two drugs to the CNS by reducing the dose to be administered (decrease side effects).

Industrial Project

Nome progetto:
Development of organic light-emitting field-effect transistors

ETC is a start up company of the SAES Group and a spin off of CNR, and was built by leveraging on the fundamental research expertise and know-how developed at ISMN. The principal focus of ETC is the development of functional materials and advanced device architectures for use in Organic Photonics applications. The project aims at investigating the fundamental properties of functional materials suitable for use as active layers in OLETs.  The basic excitonic and optoelectronic characteristics are investigated at the material and device level by advanced spectroscopic and imaging tools capable of providing a deep insight into the correlation between materials structure, processing techniques and device architectures. 

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